| Host: |
Rabbit |
| Applications: |
IHC/WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CACNA2D4 (Internal Region) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Lyophilised |
| Purification: |
IgG purified |
| Dilution Range: |
IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: |
Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: |
CACNA2D4 |
| Gene ID: |
93589 |
| Uniprot ID: |
CA2D4_HUMAN |
| Immunogen Region: |
Internal Region |
| Specificity: |
Specific for CACNA2D4. |
| Immunogen: |
A synthetic peptide from the internal region of human CACNA2D4 conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 95% identity with mouse sequence. |
| Post Translational Modifications | May be proteolytically processed into subunits alpha-2-4 and delta-4 that are disulfide-linked. It is however unclear whether such cleavage really takes place in vivo and has a functional role. |
| Function | The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. |
| Protein Name | Voltage-Dependent Calcium Channel Subunit Alpha-2/Delta-4Voltage-Gated Calcium Channel Subunit Alpha-2/Delta-4 Cleaved Into - Voltage-Dependent Calcium Channel Subunit Alpha-2-4 - Voltage-Dependent Calcium Channel Subunit Delta-4 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Voltage-Dependent Calcium Channel Subunit Alpha-2/Delta-4 antibodyAnti-Voltage-Gated Calcium Channel Subunit Alpha-2/Delta-4 Cleaved Into - Voltage-Dependent Calcium Channel Subunit Alpha-2-4 - Voltage-Dependent Calcium Channel Subunit Delta-4 antibodyAnti-CACNA2D4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
