Anti-CACNA2D4 antibody (Internal Region) (STJ13100832)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from the internal region of human CACNA2D4 conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 95% identity with mouse sequence.
General Information
| Short Description | Rabbit polyclonal anti-CACNA2D4 (Internal Region) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20ยฐC for long term storage and refrigerated at 2-8ยฐC for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | CACNA2D4 |
| Gene ID | 93589 |
| Uniprot ID | CA2D4_HUMAN |
| Immunogen | A synthetic peptide from the internal region of human CACNA2D4 conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 95% identity with mouse sequence. |
| Immunogen Region | Internal Region |
| Specificity | Specific for CACNA2D4. |
Additional Info
| Post Translational Modifications | May be proteolytically processed into subunits alpha-2-4 and delta-4 that are disulfide-linked. It is however unclear whether such cleavage really takes place in vivo and has a functional role. |
| Function | The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. |
| Protein Name | Voltage-Dependent Calcium Channel Subunit Alpha-2/Delta-4Voltage-Gated Calcium Channel Subunit Alpha-2/Delta-4 Cleaved Into - Voltage-Dependent Calcium Channel Subunit Alpha-2-4 - Voltage-Dependent Calcium Channel Subunit Delta-4 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Voltage-Dependent Calcium Channel Subunit Alpha-2/Delta-4 antibodyAnti-Voltage-Gated Calcium Channel Subunit Alpha-2/Delta-4 Cleaved Into - Voltage-Dependent Calcium Channel Subunit Alpha-2-4 - Voltage-Dependent Calcium Channel Subunit Delta-4 antibodyAnti-CACNA2D4 antibody |
Information sourced from Uniprot.org