Anti-CA5B antibody (1-317) (STJ119691)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CA5B (1-317) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CA5B |
| Gene ID | 11238 |
| Uniprot ID | CAH5B_HUMAN |
| Immunogen Region | 1-317 |
| Immunogen Sequence | MVVMNSLRVILQASPGKLLW RKFQIPRFMPARPCSLYTCT YKTRNRALHPLWESVDLVPG GDRQSPINIRWRDSVYDPGL KPLTISYDPATCLHVWNNGY SFLVEFEDSTDKSVIKGGPL EHNYRLKQFHFHWGAIDAWG SEHTVDSKCFPAELHLVHWN AVRFENFEDAALEENGLAVI GVFLKLGKHHKELQKLVDTL PSIKHKDALVEFGSFDPSCL MPTCPDYWTYSGSLTTPPL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-317 of human CA5B (NP_009151.1). |
Additional Info
| Tissue Specificity | Strongest expression in heart, pancreas, kidney, placenta, lung, and skeletal muscle. Not expressed in liver. |
| Function | Mitochondrial carbonic anhydrase that catalyzes the reversible conversion of carbon dioxide to bicarbonate/HCO3. |
| Protein Name | Carbonic Anhydrase 5b - MitochondrialCarbonate Dehydratase VbCarbonic Anhydrase VbCa-Vb |
| Database Links | Reactome: R-HSA-1475029 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Carbonic Anhydrase 5b - Mitochondrial antibodyAnti-Carbonate Dehydratase Vb antibodyAnti-Carbonic Anhydrase Vb antibodyAnti-Ca-Vb antibodyAnti-CA5B antibody |
Information sourced from Uniprot.org