| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-C-Reactive Protein/CRP (20-230) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:5000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
Crp |
| Gene ID: |
25419 |
| Uniprot ID: |
CRP_RAT |
| Immunogen Region: |
20-230 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 20-230 of rat C-Reactive Protein/CRP (NP_058792.1). |
| Immunogen Sequence: |
HEDMSKQAFVFPGVSATAYV SLEAESKKPLEAFTVCLYAH ADVSRSFSIFSYATKTSFNE ILLFWTRGQGFSIAVGGPEI LFSASEIPEVPTHICATWES ATGIVELWLDGKPRVRKSLQ KGYIVGTNASIILGQEQDSY GGGFDANQSLVGDIGDVNMW DFVLSPEQINAVYVGRVFSP NVLNWRALKYETHGDVFIKP QLWPLTDCCES |
| Tissue Specificity | Found in plasma. |
| Post Translational Modifications | The last two cysteines are involved either in interchain disulfide bonds or in an intrachain bond. |
| Function | Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. |
| Protein Name | C-Reactive Protein |
| Database Links | Reactome: R-RNO-173623 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-Reactive Protein antibodyAnti-Crp antibodyAnti-Ptx1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
