Anti-C-Reactive Protein/CRP antibody (20-230) (STJ11105370)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal C-Reactive Protein/CRP (20-230) antibody for use in WB and ELISA in rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Crp |
| Gene ID | 25419 |
| Uniprot ID | CRP_RAT |
| Immunogen Region | 20-230 |
| Immunogen Sequence | HEDMSKQAFVFPGVSATAYV SLEAESKKPLEAFTVCLYAH ADVSRSFSIFSYATKTSFNE ILLFWTRGQGFSIAVGGPEI LFSASEIPEVPTHICATWES ATGIVELWLDGKPRVRKSLQ KGYIVGTNASIILGQEQDSY GGGFDANQSLVGDIGDVNMW DFVLSPEQINAVYVGRVFSP NVLNWRALKYETHGDVFIKP QLWPLTDCCES |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 20-230 of rat C-Reactive Protein/CRP (NP_058792.1). |
Additional Info
| Tissue Specificity | Found in plasma. |
| Post Translational Modifications | The last two cysteines are involved either in interchain disulfide bonds or in an intrachain bond. |
| Function | Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. |
| Protein Name | C-Reactive Protein |
| Database Links | Reactome: R-RNO-173623 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-Reactive Protein antibodyAnti-Crp antibodyAnti-Ptx1 antibody |
Information sourced from Uniprot.org