| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | Crp |
| Gene ID: | 25419 |
| Uniprot ID: | CRP_RAT |
| Immunogen Region: | 20-230 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-230 of rat C-Reactive Protein/CRP (NP_058792.1). |
| Immunogen Sequence: | HEDMSKQAFVFPGVSATAYV SLEAESKKPLEAFTVCLYAH ADVSRSFSIFSYATKTSFNE ILLFWTRGQGFSIAVGGPEI LFSASEIPEVPTHICATWES ATGIVELWLDGKPRVRKSLQ KGYIVGTNASIILGQEQDSY GGGFDANQSLVGDIGDVNMW DFVLSPEQINAVYVGRVFSP NVLNWRALKYETHGDVFIKP QLWPLTDCCES |
| Tissue Specificity | Found in plasma. |
| Post Translational Modifications | The last two cysteines are involved either in interchain disulfide bonds or in an intrachain bond. |
| Function | Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. |
| Protein Name | C-Reactive Protein |
| Database Links | Reactome: R-RNO-173623 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-Reactive Protein antibodyAnti-Crp antibodyAnti-Ptx1 antibody |
Information sourced from Uniprot.org
