Anti-Artemin antibody [2D12] (STJA0002897)

SKU:
STJA0002897-500

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Host: Mouse
Applications: ELISA/WB/IF
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Artemin is suitable for use in ELISA, Western Blot and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: 2D12
Conjugation: Unconjugated
Isotype: IgG1
Formulation: PBS pH 7.4, with 0.1% sodium azide
Purification: Protein G purification
Dilution Range: ELISA 0.2 to 2 µg/ml; WB 0.5 to 2 µg/ml (detects only dimeric protein in non-reducing conditions) ; IF 0.3 to 20 µg/ml. Monoclonal antibody working titer has to be established practically for each particular antigen and assay format
Storage Instruction: Store at-20 to-70°C upon receipt. Divide antibody into aliquots prior usage. Avoid multiple freeze-thaw cycles
Gene Symbol: ARTN
Gene ID: 9048
Uniprot ID: ARTN_HUMAN
Specificity: Human Artemin
Immunogen: Recombinant human Artemin protein produced using CHO-based proprietary suspension cell line. Immunogen is purified from cell culture supernatant. Human Artemin
Tissue Specificity Ubiquitous. Expressed at high levels in peripheral tissues including prostate, placenta, pancreas, heart, kidney, pituitary gland, lung and testis. Expressed at low levels in the brain.
Function Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue.
Protein Name Artemin
Enovin
Neublastin
Database Links Reactome: R-HSA-419037
Reactome: R-HSA-5673001
Reactome: R-HSA-8853659
Cellular Localisation Secreted
Alternative Antibody Names Anti-Artemin antibody
Anti-Enovin antibody
Anti-Neublastin antibody
Anti-ARTN antibody
Anti-EVN antibody

Information sourced from Uniprot.org

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