![Immunofluorescence analysis of HeLa cells using [KO Validated] Annexin A5/Annexin V Rabbit polyclonal antibody (STJ22620) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/99134/383749/STJ22620_1__87132.1713152313.jpg?c=1 "Immunofluorescence analysis of HeLa cells using [KO Validated] Annexin A5/Annexin V Rabbit polyclonal antibody (STJ22620) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.")
![Immunofluorescence analysis of HeLa cells using [KO Validated] Annexin A5/Annexin V Rabbit polyclonal antibody (STJ22620) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/99134/383749/STJ22620_1__87132.1713152313.jpg?c=1 "Immunofluorescence analysis of HeLa cells using [KO Validated] Annexin A5/Annexin V Rabbit polyclonal antibody (STJ22620) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.")
Anti-ANXA5 antibody (1-320) (STJ22620)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ANXA5 (1-320) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ANXA5 |
| Gene ID | 308 |
| Uniprot ID | ANXA5_HUMAN |
| Immunogen Region | 1-320 |
| Immunogen Sequence | MAQVLRGTVTDFPGFDERAD AETLRKAMKGLGTDEESILT LLTSRSNAQRQEISAAFKTL FGRDLLDDLKSELTGKFEKL IVALMKPSRLYDAYELKHAL KGAGTNEKVLTEIIASRTPE ELRAIKQVYEEEYGSSLEDD VVGDTSGYYQRMLVVLLQAN RDPDAGIDEAQVEQDAQALF QAGELKWGTDEEKFITIFGT RSVSHLRKVFDKYMTISGFQ IEETIDRETSGNLEQLLLA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human Annexin A5/Annexin V (NP_001145.1). |
Additional Info
| Post Translational Modifications | S-nitrosylation is induced by interferon-gamma and oxidatively-modified low-densitity lipoprotein (LDL(ox)) possibly implicating the iNOS-S100A8/9 transnitrosylase complex. |
| Function | This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. |
| Protein Name | Annexin A5Anchorin CiiAnnexin VAnnexin-5Calphobindin ICpb-IEndonexin IiLipocortin VPlacental Anticoagulant Protein 4Pp4Placental Anticoagulant Protein IPap-IThromboplastin InhibitorVascular Anticoagulant-AlphaVac-Alpha |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Annexin A5 antibodyAnti-Anchorin Cii antibodyAnti-Annexin V antibodyAnti-Annexin-5 antibodyAnti-Calphobindin I antibodyAnti-Cpb-I antibodyAnti-Endonexin Ii antibodyAnti-Lipocortin V antibodyAnti-Placental Anticoagulant Protein 4 antibodyAnti-Pp4 antibodyAnti-Placental Anticoagulant Protein I antibodyAnti-Pap-I antibodyAnti-Thromboplastin Inhibitor antibodyAnti-Vascular Anticoagulant-Alpha antibodyAnti-Vac-Alpha antibodyAnti-ANXA5 antibodyAnti-ANX5 antibodyAnti-ENX2 antibodyAnti-PP4 antibody |
Information sourced from Uniprot.org