![Immunofluorescence analysis of HeLa cells using [KO Validated] Annexin A5/Annexin V Rabbit polyclonal antibody (STJ22620) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/99134/383749/STJ22620_1__87132.1713152313.jpg?c=1 "Immunofluorescence analysis of HeLa cells using [KO Validated] Annexin A5/Annexin V Rabbit polyclonal antibody (STJ22620) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.")
![Immunofluorescence analysis of HeLa cells using [KO Validated] Annexin A5/Annexin V Rabbit polyclonal antibody (STJ22620) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/99134/383749/STJ22620_1__87132.1713152313.jpg?c=1 "Immunofluorescence analysis of HeLa cells using [KO Validated] Annexin A5/Annexin V Rabbit polyclonal antibody (STJ22620) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.")
| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ANXA5 |
| Gene ID: | 308 |
| Uniprot ID: | ANXA5_HUMAN |
| Immunogen Region: | 1-320 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human Annexin A5/Annexin V (NP_001145.1). |
| Immunogen Sequence: | MAQVLRGTVTDFPGFDERAD AETLRKAMKGLGTDEESILT LLTSRSNAQRQEISAAFKTL FGRDLLDDLKSELTGKFEKL IVALMKPSRLYDAYELKHAL KGAGTNEKVLTEIIASRTPE ELRAIKQVYEEEYGSSLEDD VVGDTSGYYQRMLVVLLQAN RDPDAGIDEAQVEQDAQALF QAGELKWGTDEEKFITIFGT RSVSHLRKVFDKYMTISGFQ IEETIDRETSGNLEQLLLA |
| Post Translational Modifications | S-nitrosylation is induced by interferon-gamma and oxidatively-modified low-densitity lipoprotein (LDL(ox)) possibly implicating the iNOS-S100A8/9 transnitrosylase complex. |
| Function | This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. |
| Protein Name | Annexin A5 Anchorin Cii Annexin V Annexin-5 Calphobindin I Cpb-I Endonexin Ii Lipocortin V Placental Anticoagulant Protein 4 Pp4 Placental Anticoagulant Protein I Pap-I Thromboplastin Inhibitor Vascular Anticoagulant-Alpha Vac-Alpha |
| Database Links | Reactome: R-HSA-114608 |
| Alternative Antibody Names | Anti-Annexin A5 antibody Anti-Anchorin Cii antibody Anti-Annexin V antibody Anti-Annexin-5 antibody Anti-Calphobindin I antibody Anti-Cpb-I antibody Anti-Endonexin Ii antibody Anti-Lipocortin V antibody Anti-Placental Anticoagulant Protein 4 antibody Anti-Pp4 antibody Anti-Placental Anticoagulant Protein I antibody Anti-Pap-I antibody Anti-Thromboplastin Inhibitor antibody Anti-Vascular Anticoagulant-Alpha antibody Anti-Vac-Alpha antibody Anti-ANXA5 antibody Anti-ANX5 antibody Anti-ENX2 antibody Anti-PP4 antibody |
Information sourced from Uniprot.org