Anti-ADGRG5 antibody (91-140 aa) (STJ93322)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human GPR114 at the amino acid range 91-140
General Information
| Short Description | Rabbit polyclonal anti-Adhesion G-protein coupled receptor G5 (91-140 aa) for use in WB, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:5000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ADGRG5 |
| Gene ID | 221188 |
| Uniprot ID | AGRG5_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human GPR114 at the amino acid range 91-140 |
| Immunogen Region | 91-140 aa |
| Specificity | GPR114 Polyclonal Antibody detects endogenous levels of GPR114 protein. |
Additional Info
| Post Translational Modifications | Autoproteolytically processed at the GPS region of the GAIN-B domain.this cleavage modulates receptor activity. N-glycsylated. |
| Function | Orphan adhesion G-protein coupled receptor (aGPCR). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRG5 is specifically coupled to G(s) G proteins and mediates activation of adenylate cyclase activity. |
| Protein Name | Adhesion G-Protein Coupled Receptor G5G-Protein Coupled Receptor 114G-Protein Coupled Receptor Pgr27 Cleaved Into - Adhesion G-Protein Coupled Receptor G5 - N-Terminal FragmentAdgrg5 N-Terminal Fragment - Adhesion G-Protein Coupled Receptor G5 - C-Terminal FragmentAdgrg5 C-Terminal Fragment |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Adhesion G-Protein Coupled Receptor G5 antibodyAnti-G-Protein Coupled Receptor 114 antibodyAnti-G-Protein Coupled Receptor Pgr27 Cleaved Into - Adhesion G-Protein Coupled Receptor G5 - N-Terminal Fragment antibodyAnti-Adgrg5 N-Terminal Fragment - Adhesion G-Protein Coupled Receptor G5 - C-Terminal Fragment antibodyAnti-Adgrg5 C-Terminal Fragment antibodyAnti-ADGRG5 antibodyAnti-GPR114 antibodyAnti-PGR27 antibodyAnti-UNQ2524 antibodyAnti-PRO6017 antibody |
Information sourced from Uniprot.org