• Western blot analysis of lysates from COLO205 cells, using GPR114 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of the lysates from 293 cells using GPR114 antibody.
  • Western blot analysis of COLO205 cells using GPR114 Polyclonal Antibody

Anti-ADGRG5 antibody (91-140 aa) (STJ93322)

SKU:
STJ93322

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Adhesion G-protein coupled receptor G5 (91-140 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ADGRG5
Gene ID: 221188
Uniprot ID: AGRG5_HUMAN
Immunogen Region: 91-140 aa
Specificity: GPR114 Polyclonal Antibody detects endogenous levels of GPR114 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human GPR114 at the amino acid range 91-140
Post Translational Modifications Autoproteolysis between residues Leu-226 and Thr-227 occurs in the lumen of the endoplasmic reticulum during receptor biosynthesis. The N-terminal fragment (NTF) subsequently reassociates with the C-terminal fragment (CTF) either in a homogeneric heterodimerization, or with another family member through heterogeneric heterodimerization. Autocatalytic cleavage is thought to be critical for the maturation, stability, trafficking, and function.
Function Adhesion G protein-coupled receptor (GPCR). Transduces intracellular signals through coupling to guanine nucleotide-binding protein G(s) subunit alpha and activation of adenylate cyclase pathway. Isoform 1, but not isoform 2, is constitutively active, as evidenced by elevated basal cAMP levels, and responds to mechanical activation (shaking).
Protein Name Adhesion G-Protein Coupled Receptor G5
G-Protein Coupled Receptor 114
G-Protein Coupled Receptor Pgr27
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Adhesion G-Protein Coupled Receptor G5 antibody
Anti-G-Protein Coupled Receptor 114 antibody
Anti-G-Protein Coupled Receptor Pgr27 antibody
Anti-ADGRG5 antibody
Anti-GPR114 antibody
Anti-PGR27 antibody
Anti-UNQ2524 antibody
Anti-PRO6017 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance