| Post Translational Modifications | Autoproteolytically processed at the GPS region of the GAIN-B domain.this cleavage modulates receptor activity. N-glycsylated. |
| Function | Orphan adhesion G-protein coupled receptor (aGPCR). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRG5 is specifically coupled to G(s) G proteins and mediates activation of adenylate cyclase activity. |
| Protein Name | Adhesion G-Protein Coupled Receptor G5G-Protein Coupled Receptor 114G-Protein Coupled Receptor Pgr27 Cleaved Into - Adhesion G-Protein Coupled Receptor G5 - N-Terminal FragmentAdgrg5 N-Terminal Fragment - Adhesion G-Protein Coupled Receptor G5 - C-Terminal FragmentAdgrg5 C-Terminal Fragment |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Adhesion G-Protein Coupled Receptor G5 antibodyAnti-G-Protein Coupled Receptor 114 antibodyAnti-G-Protein Coupled Receptor Pgr27 Cleaved Into - Adhesion G-Protein Coupled Receptor G5 - N-Terminal Fragment antibodyAnti-Adgrg5 N-Terminal Fragment - Adhesion G-Protein Coupled Receptor G5 - C-Terminal Fragment antibodyAnti-Adgrg5 C-Terminal Fragment antibodyAnti-ADGRG5 antibodyAnti-GPR114 antibodyAnti-PGR27 antibodyAnti-UNQ2524 antibodyAnti-PRO6017 antibody |
Information sourced from Uniprot.org