Synaptotagmin 1 Blocking Peptide peptide (STJ504978)

SKU:
STJ504978-250

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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Synaptotagmin 1 Blocking Peptide is synthetically produced from the 1-60 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: SYT1
Gene ID: 6857
Uniprot ID: SYT1_HUMAN
Immunogen Region: 1-60
Immunogen: Synthetic peptide taken within amino acid region 1-60 on SYT1 protein.
Tissue Specificity Expressed in melanocytes.
Post Translational Modifications Glycosylated.
Function Calcium sensor that participates in triggering neurotransmitter release at the synapse. May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner.these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes.
Peptide Name Synaptotagmin-1
Synaptotagmin I
Syti
P65
Database Links Reactome: R-HSA-181429
Reactome: R-HSA-181430
Reactome: R-HSA-210500
Reactome: R-HSA-212676
Reactome: R-HSA-264642
Reactome: R-HSA-5250958
Reactome: R-HSA-5250989
Reactome: R-HSA-6794361
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Reactome: R-HSA-888590
Cellular Localisation Cytoplasmic Vesicle
Secretory Vesicle Membrane
Single-Pass Membrane Protein
Secretory Vesicle
Synaptic Vesicle Membrane
Chromaffin Granule Membrane
Cytoplasm
Alternative Peptide Names Synaptotagmin-1 protein
Synaptotagmin I protein
Syti protein
P65 protein
SYT1 protein
SVP65 protein
SYT protein

Information sourced from Uniprot.org

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