Function | Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation. In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling. |
Peptide Name | Tyrosine-Protein Kinase Transmembrane Receptor Ror2Neurotrophic Tyrosine Kinase - Receptor-Related 2 |
Database Links | Reactome: R-HSA-4086400Reactome: R-HSA-5140745 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Peptide Names | Tyrosine-Protein Kinase Transmembrane Receptor Ror2 proteinNeurotrophic Tyrosine Kinase - Receptor-Related 2 proteinROR2 proteinNTRKR2 protein |
Information sourced from Uniprot.org