ROR2 Positive Control for STJ502829 peptide (STJ505105)
SPECIFICATIONS
General Information
| Short Description | ROR2 Positive Control for STJ502829 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | WB |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | WB: 1:500 |
| Formulation | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | ROR2 |
| Gene ID | 4920 |
| Uniprot ID | ROR2_HUMAN |
| Specificity | This is positive control is recommended for use in combination with ROR2 antibody STJ502829. |
Additional Info
| Function | Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation. In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling. |
| Peptide Name | Tyrosine-Protein Kinase Transmembrane Receptor Ror2Neurotrophic Tyrosine Kinase - Receptor-Related 2 |
| Database Links | Reactome: R-HSA-4086400Reactome: R-HSA-5140745 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Peptide Names | Tyrosine-Protein Kinase Transmembrane Receptor Ror2 proteinNeurotrophic Tyrosine Kinase - Receptor-Related 2 proteinROR2 proteinNTRKR2 protein |
Information sourced from Uniprot.org