Rat GFRa1 (Gdnf Family Receptor Alpha-1) Antibody Pair (STJAP00361)
SPECIFICATIONS
ClonalityMonoclonal/Polyclonal
HostMouse/Goat
ConjugationUnconjugated/Biotin
ImmunogenCapture immunogen: Recombinant Rat GFRa1 protein.Detection Immunogen: Recombinant Rat GFRa1 protein.
General Information
| Short Description | This GFRa1 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Mouse/Goat |
| Reactivity | Rat |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Polyclonal |
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Protein A or G.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | Gfra1 |
| Gene ID | 25454 |
| Uniprot ID | GFRA1_RAT |
| Immunogen | Capture immunogen: Recombinant Rat GFRa1 protein.Detection Immunogen: Recombinant Rat GFRa1 protein. |
Additional Info
| Function | Coreceptor for GDNF, a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. GDNF-binding leads to autophosphorylation and activation of the RET receptor. |
| Protein Name | Gdnf Family Receptor Alpha-1Gdnf Receptor Alpha-1Gdnfr-Alpha-1Gfr-Alpha-1Ret Ligand 1Tgf-Beta-Related Neurotrophic Factor Receptor 1 |
| Database Links | Reactome: R-RNO-5673001Reactome: -RNO-8853659 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorGolgi ApparatusTrans-Golgi NetworkEndosomeMultivesicular BodyLocalizes Mainly To The Plasma MembraneIn The Presence Of Sorl1Shifts To Vesicular StructuresIncluding Trans-Golgi NetworkEndosomes And Multivesicular Bodies |
| Alternative Antibody Pair Names | Gdnf Family Receptor Alpha-1 antibody pairGdnf Receptor Alpha-1 antibody pairGdnfr-Alpha-1 antibody pairGfr-Alpha-1 antibody pairRet Ligand 1 antibody pairTgf-Beta-Related Neurotrophic Factor Receptor 1 antibody pairGfra1 antibody pairGdnfra antibody pairRetl1 antibody pairTrnr1 antibody pair |
Information sourced from Uniprot.org