Rat GFRa1 (Gdnf Family Receptor Alpha-1) Antibody Pair (STJAP00361)

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STJAP00361-50
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Host: Mouse/Goat
Applications: ELISA
Reactivity: Rat
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description : This GFRa1 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA.
Clonality : Monoclonal/Polyclonal
Conjugation: Unconjugated/Biotin
Formulation: Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Purification: Capture Purification: Protein A or G.
Detection Purification: Antigen Affinity.
Concentration: 0.5 mg/mL
Storage Instruction: Store at-20°C for long term, and avoid freeze-thaw cycles.
Gene Symbol: Gfra1
Gene ID: 25454
Uniprot ID: GFRA1_RAT
Immunogen: Capture immunogen: Recombinant Rat GFRa1 protein.
Detection Immunogen: Recombinant Rat GFRa1 protein.
Function Coreceptor for GDNF, a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. GDNF-binding leads to autophosphorylation and activation of the RET receptor.
Protein Name Gdnf Family Receptor Alpha-1
Gdnf Receptor Alpha-1
Gdnfr-Alpha-1
Gfr-Alpha-1
Ret Ligand 1
Tgf-Beta-Related Neurotrophic Factor Receptor 1
Database Links Reactome: R-RNO-5673001
Reactome: -RNO-8853659
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Golgi Apparatus
Trans-Golgi Network
Endosome
Multivesicular Body
Localizes Mainly To The Plasma Membrane
In The Presence Of Sorl1
Shifts To Vesicular Structures
Including Trans-Golgi Network
Endosomes And Multivesicular Bodies
Alternative Antibody Pair Names Gdnf Family Receptor Alpha-1 antibody pair
Gdnf Receptor Alpha-1 antibody pair
Gdnfr-Alpha-1 antibody pair
Gfr-Alpha-1 antibody pair
Ret Ligand 1 antibody pair
Tgf-Beta-Related Neurotrophic Factor Receptor 1 antibody pair
Gfra1 antibody pair
Gdnfra antibody pair
Retl1 antibody pair
Trnr1 antibody pair

Information sourced from Uniprot.org

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