PDE7A Blocking Peptide for STJ502625 peptide (STJ504666)
SPECIFICATIONS
ImmunogenSynthetic cyclic peptide common to PDE7A1 and PDE7A2 variants.
General Information
| Short Description | PDE7A Blocking Peptide for STJ502625 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | PDE7A |
| Gene ID | 5150 |
| Uniprot ID | PDE7A_HUMAN |
| Immunogen | Synthetic cyclic peptide common to PDE7A1 and PDE7A2 variants. |
| Specificity | This blocking peptide is recommended for use in combination with PDE7A antibody, STJ502625 |
Additional Info
| Tissue Specificity | Isoform PDE7A1: Found at high levels in skeletal muscle and at low levels in a variety of tissues including brain and heart. It is expressed as well in two T-cell lines. Isoform PDE7A2: Found abundantly in skeletal muscle and at low levels in heart. |
| Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle signal transduction. |
| Peptide Name | High Affinity 3' -5'-Cyclic-Amp Phosphodiesterase 7aHcp1Tm22Camp-Specific Phosphodiesterase 7a |
| Database Links | Reactome: R-HSA-418555 |
| Cellular Localisation | Isoform Pde7a1: CytoplasmCytosolPde7a1 (57 Kda) Is Located Mostly To Soluble Cellular FractionsIsoform Pde7a2: CytoplasmPde7a2 (50 Kda) Is Located To Particulate Cellular Fractions |
| Alternative Peptide Names | High Affinity 3' -5'-Cyclic-Amp Phosphodiesterase 7a proteinHcp1 proteinTm22 proteinCamp-Specific Phosphodiesterase 7a proteinPDE7A protein |
Information sourced from Uniprot.org