Applications: |
Immunodepletion/Immunocompetition |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
PDE7A Blocking Peptide for STJ502625 is synthetically produced from the sequence and is suitable for use in western blot applications. |
Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
PDE7A |
Gene ID: |
5150 |
Uniprot ID: |
PDE7A_HUMAN |
Specificity: |
This blocking peptide is recommended for use in combination with PDE7A antibody, STJ502625 |
Immunogen: |
Synthetic cyclic peptide common to PDE7A1 and PDE7A2 variants. |
Tissue Specificity | Isoform PDE7A1: Found at high levels in skeletal muscle and at low levels in a variety of tissues including brain and heart. It is expressed as well in two T-cell lines. Isoform PDE7A2: Found abundantly in skeletal muscle and at low levels in heart. |
Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle signal transduction. |
Peptide Name | High Affinity Camp-Specific 3' -5'-Cyclic Phosphodiesterase 7aHcp1Tm22 |
Database Links | Reactome: R-HSA-418555 |
Cellular Localisation | Isoform Pde7a1: CytoplasmCytosolPde7a1 (57 Kda) Is Located Mostly To Soluble Cellular FractionsIsoform Pde7a2: CytoplasmPde7a2 (50 Kda) Is Located To Particulate Cellular Fractions |
Alternative Peptide Names | High Affinity Camp-Specific 3' -5'-Cyclic Phosphodiesterase 7a proteinHcp1 proteinTm22 proteinPDE7A protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance