PDE4D7 Blocking Peptide for STJ502341 peptide (STJ504651)
SPECIFICATIONS
ImmunogenSynthetic peptide corresponding to unique amino acid sequence on PDE4D7 variant.
General Information
| Short Description | PDE4D7 Blocking Peptide for STJ502341 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | Pde4d |
| Gene ID | 238871 |
| Uniprot ID | PDE4D_MOUSE |
| Immunogen | Synthetic peptide corresponding to unique amino acid sequence on PDE4D7 variant. |
| Specificity | This blocking peptide is recommended for use in combination with PDE4D7 antibody, STJ502341 |
Additional Info
| Tissue Specificity | Expressed in brain (at protein level). Isoform 7 is detected in heart, brain, lung, kidney and testis. |
| Post Translational Modifications | Sumoylation of long isoforms by PIAS4 augments their activation by PKA phosphorylation and represses their inhibition by ERK phosphorylation. |
| Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. |
| Peptide Name | 3' -5'-Cyclic-Amp Phosphodiesterase 4dDpde3Camp-Specific Phosphodiesterase 4d |
| Database Links | Reactome: R-MMU-180024Reactome: -MMU-418555 |
| Cellular Localisation | CytoplasmMembraneCytoskeletonMicrotubule Organizing CenterCentrosomeApical Cell MembraneColocalized With Shank2 To The Apical Membrane Of Colonic Crypt CellsFound In The Soluble FractionAssociated With MembranesAnd Associated With The Cytoskeleton And The Centrosome |
| Alternative Peptide Names | 3' -5'-Cyclic-Amp Phosphodiesterase 4d proteinDpde3 proteinCamp-Specific Phosphodiesterase 4d proteinPde4d protein |
Information sourced from Uniprot.org