| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
PDE4D7 Blocking Peptide for STJ502341 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
Pde4d |
| Gene ID: |
238871 |
| Uniprot ID: |
PDE4D_MOUSE |
| Specificity: |
This blocking peptide is recommended for use in combination with PDE4D7 antibody, STJ502341 |
| Immunogen: |
Synthetic peptide corresponding to unique amino acid sequence on PDE4D7 variant. |
| Tissue Specificity | Expressed in brain (at protein level). Isoform 7 is detected in heart, brain, lung, kidney and testis. |
| Post Translational Modifications | Sumoylation of long isoforms by PIAS4 augments their activation by PKA phosphorylation and represses their inhibition by ERK phosphorylation. |
| Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. |
| Peptide Name | Camp-Specific 3' -5'-Cyclic Phosphodiesterase 4dDpde3 |
| Database Links | Reactome: R-MMU-180024Reactome: -MMU-418555 |
| Cellular Localisation | CytoplasmMembraneCytoskeletonMicrotubule Organizing CenterCentrosomeApical Cell MembraneColocalized With Shank2 To The Apical Membrane Of Colonic Crypt CellsFound In The Soluble FractionAssociated With MembranesAnd Associated With The Cytoskeleton And The Centrosome |
| Alternative Peptide Names | Camp-Specific 3' -5'-Cyclic Phosphodiesterase 4d proteinDpde3 proteinPde4d protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
