PACAP Positive Control peptide (STJ505621)
SPECIFICATIONS
ImmunogenPurfied protein.
General Information
| Short Description | PACAP Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | WB |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | WB: 1:2, 500-1:5, 000 |
| Formulation | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | ADCYAP1 |
| Gene ID | 116 |
| Uniprot ID | PACA_HUMAN |
| Immunogen | Purfied protein. |
Additional Info
| Function | Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells. |
| Peptide Name | Pituitary Adenylate Cyclase-Activating PolypeptidePacap Cleaved Into - Pacap-Related PeptidePrp-48 - Pituitary Adenylate Cyclase-Activating Polypeptide 27Pacap-27Pacap27 - Pituitary Adenylate Cyclase-Activating Polypeptide 38Pacap-38Pacap38 |
| Database Links | Reactome: R-HSA-187024Reactome: R-HSA-418555Reactome: R-HSA-420092 |
| Cellular Localisation | Secreted |
| Alternative Peptide Names | Pituitary Adenylate Cyclase-Activating Polypeptide proteinPacap Cleaved Into - Pacap-Related Peptide proteinPrp-48 - Pituitary Adenylate Cyclase-Activating Polypeptide 27 proteinPacap-27 proteinPacap27 - Pituitary Adenylate Cyclase-Activating Polypeptide 38 proteinPacap-38 proteinPacap38 proteinADCYAP1 protein |
Information sourced from Uniprot.org