PACAP Positive Control peptide (STJ505621)

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STJ505621-5
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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : PACAP Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:2, 500-1:5, 000
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: ADCYAP1
Gene ID: 116
Uniprot ID: PACA_HUMAN
Immunogen: Purfied protein.
Function Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells.
Peptide Name Pituitary Adenylate Cyclase-Activating Polypeptide
Pacap Cleaved Into - Pacap-Related Peptide
Prp-48 - Pituitary Adenylate Cyclase-Activating Polypeptide 27
Pacap-27
Pacap27 - Pituitary Adenylate Cyclase-Activating Polypeptide 38
Pacap-38
Pacap38
Database Links Reactome: R-HSA-187024
Reactome: R-HSA-418555
Reactome: R-HSA-420092
Cellular Localisation Secreted
Alternative Peptide Names Pituitary Adenylate Cyclase-Activating Polypeptide protein
Pacap Cleaved Into - Pacap-Related Peptide protein
Prp-48 - Pituitary Adenylate Cyclase-Activating Polypeptide 27 protein
Pacap-27 protein
Pacap27 - Pituitary Adenylate Cyclase-Activating Polypeptide 38 protein
Pacap-38 protein
Pacap38 protein
ADCYAP1 protein

Information sourced from Uniprot.org

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