Olig2 Blocking Peptide peptide (STJ504435)

Name: Olig2 Blocking Peptide peptide (STJ504435)
SKU: STJ504435-250
Price: 359.49 USD
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ImmunogenSynthetic peptide taken within amino acid region 1-50 on human Olig2 protein.

STJ504435-250

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Short Description	Olig2 Blocking Peptide is synthetically produced from the 1-50 sequence and is suitable for use in western blot applications.
Applications	Immunodepletion/Immunocompetition
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Formulation	Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol	OLIG2
Gene ID	10215
Uniprot ID	OLIG2_HUMAN
Immunogen	Synthetic peptide taken within amino acid region 1-50 on human Olig2 protein.
Immunogen Region	1-50

Tissue Specificity	Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.
Function	Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Functions together with ZNF488 to promote oligodendrocyte differentiation. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development.
Peptide Name	Oligodendrocyte Transcription Factor 2 Oligo2 Class B Basic Helix-Loop-Helix Protein 1 Bhlhb1 Class E Basic Helix-Loop-Helix Protein 19 Bhlhe19 Protein Kinase C-Binding Protein 2 Protein Kinase C-Binding Protein Rack17
Cellular Localisation	Nucleus Cytoplasm The Nls Contained In The Bhlh Domain Could Be Masked In The Native Form And Translocation To The Nucleus Could Be Mediated By Interaction Either With Class E Bhlh Partner Protein Or With Nkx2-2
Alternative Peptide Names	Oligodendrocyte Transcription Factor 2 protein Oligo2 protein Class B Basic Helix-Loop-Helix Protein 1 protein Bhlhb1 protein Class E Basic Helix-Loop-Helix Protein 19 protein Bhlhe19 protein Protein Kinase C-Binding Protein 2 protein Protein Kinase C-Binding Protein Rack17 protein OLIG2 protein BHLHB1 protein BHLHE19 protein PRKCBP2 protein RACK17 protein

Information sourced from Uniprot.org