Host: |
HEK293 |
Note: |
STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Mouse PSMA/FOLH1-N-His protein was developed from hek293 and has a target region of N-His. For use in research applications. |
Conjugation: |
Biotin |
Formulation: |
Lyophilised from 0.2 µm filtered PBS solution pH7.4. |
Dilution Range: |
Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM |
Storage Instruction: |
The lyophilized protein is stable for at least 1 year from date of receipt at-20°C. |
Endotoxin: |
Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). |
Gene Symbol: |
Folh1 |
Gene ID: |
53320 |
Uniprot ID: |
FOLH1_MOUSE |
Immunogen Region: |
Lys45-Ala752 |
Immunogen: |
DNA sequence encoding Mouse PSMA/FOLH1 (Primary Amine Labeling) including a N-His tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology. |
Function | Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC. |
Protein Name | Glutamate Carboxypeptidase 2Folate Hydrolase 1Folylpoly-Gamma-Glutamate CarboxypeptidaseFgcpGlutamate Carboxypeptidase IiGcpiiMembrane Glutamate CarboxypeptidaseMgcpN-Acetylated-Alpha-Linked Acidic Dipeptidase INaaladase IProstate-Specific Membrane Antigen HomologPteroylpoly-Gamma-Glutamate Carboxypeptidase |
Database Links | Reactome: R-MMU-8963693 |
Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
Alternative Protein Names | Glutamate Carboxypeptidase 2 proteinFolate Hydrolase 1 proteinFolylpoly-Gamma-Glutamate Carboxypeptidase proteinFgcp proteinGlutamate Carboxypeptidase Ii proteinGcpii proteinMembrane Glutamate Carboxypeptidase proteinMgcp proteinN-Acetylated-Alpha-Linked Acidic Dipeptidase I proteinNaaladase I proteinProstate-Specific Membrane Antigen Homolog proteinPteroylpoly-Gamma-Glutamate Carboxypeptidase proteinFolh1 proteinMopsm proteinNaalad1 protein |
Information sourced from Uniprot.org
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