Mouse PSMA/FOLH1 protein (Recombinant) (N-His) {Biotin} (STJP001647)
SPECIFICATIONS
HostHEK293
ConjugationBiotin
ImmunogenDNA sequence encoding Mouse PSMA/FOLH1 (Primary Amine Labeling) including a N-His tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
General Information
| Short Description | Recombinant-Mouse PSMA/FOLH1-N-His protein was developed from hek293 and has a target region of N-His. For use in research applications. |
| Host | HEK293 |
| Note | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Biotin |
| Dilution Range | Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM |
| Formulation | Lyophilised from 0.2 µm filtered PBS solution pH7.4. |
| Storage Instruction | The lyophilized protein is stable for at least 1 year from date of receipt at-20°C. |
| Endotoxin | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). |
Target Information
| Gene Symbol | Folh1 |
| Gene ID | 53320 |
| Uniprot ID | FOLH1_MOUSE |
| Immunogen | DNA sequence encoding Mouse PSMA/FOLH1 (Primary Amine Labeling) including a N-His tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology. |
| Immunogen Region | Lys45-Ala752 |
Additional Info
| Function | Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC. |
| Protein Name | Glutamate Carboxypeptidase 2Folate Hydrolase 1Folylpoly-Gamma-Glutamate CarboxypeptidaseFgcpGlutamate Carboxypeptidase IiGcpiiMembrane Glutamate CarboxypeptidaseMgcpN-Acetylated-Alpha-Linked Acidic Dipeptidase INaaladase IProstate-Specific Membrane Antigen HomologPteroylpoly-Gamma-Glutamate Carboxypeptidase |
| Database Links | Reactome: R-MMU-8963693 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Protein Names | Glutamate Carboxypeptidase 2 proteinFolate Hydrolase 1 proteinFolylpoly-Gamma-Glutamate Carboxypeptidase proteinFgcp proteinGlutamate Carboxypeptidase Ii proteinGcpii proteinMembrane Glutamate Carboxypeptidase proteinMgcp proteinN-Acetylated-Alpha-Linked Acidic Dipeptidase I proteinNaaladase I proteinProstate-Specific Membrane Antigen Homolog proteinPteroylpoly-Gamma-Glutamate Carboxypeptidase proteinFolh1 proteinMopsm proteinNaalad1 protein |
Information sourced from Uniprot.org