Mouse NUCB1 (Nucleobindin 1) Sandwich ELISA Kit (STJE0011139)

SPECIFICATIONS
STJE0011139
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General Information

Short DescriptionThis NUCB1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates or other biological fluids..
ApplicationsELISA
ReactivityMouse
Sensitivity0.059ng/mL
Detection Limit0.156-10ng/mL
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Storage InstructionStore the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time4.5 hrs

Target Information

Gene SymbolNucb1
Gene ID18220
Uniprot IDNUCB1_MOUSE
Sample Typetissue homogenates or other biological fluids.

Additional Info

Tissue Specificity Lymphoid cells as well as other somatic cells, such as liver and kidney cells.
Post Translational Modifications
Function Major calcium-binding protein of the Golgi which may have a role in calcium homeostasis. Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates alpha subunits of guanine nucleotide-binding proteins (G proteins).
Protein Name Nucleobindin-1
Calnuc
Database Links Reactome: R-MMU-381426
Reactome: -MMU-8957275
Cellular Localisation Golgi Apparatus
Cis-Golgi Network Membrane
Peripheral Membrane Protein
Lumenal Side
Cytoplasm
Secreted
A Small Fraction Of The Protein May Be Cytoplasmic
In Bone At Least Part Of It Is Found In The Extracellular Matrix And In The Culture Medium Of Calvaria Explants
In Lupus Prone
But Not In Normal Mice
At Least Part Of It Is In The Serum Where It Induces The Formation Of Autoantibodies Including Anti-Dna Antibodies
Alternative ELISA Names Nucleobindin-1 ELISA kit
Calnuc ELISA kit
Nucb1 ELISA kit
Nuc ELISA kit
Nucb ELISA kit
output

Information sourced from Uniprot.org

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