| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.059ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This NUCB1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates or other biological fluids.. |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Nucb1 |
| Gene ID: |
18220 |
| Uniprot ID: |
NUCB1_MOUSE |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Lymphoid cells as well as other somatic cells, such as liver and kidney cells. |
| Post Translational Modifications | |
| Function | Major calcium-binding protein of the Golgi which may have a role in calcium homeostasis. Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates alpha subunits of guanine nucleotide-binding proteins (G proteins). |
| Protein Name | Nucleobindin-1Calnuc |
| Database Links | Reactome: R-MMU-381426Reactome: -MMU-8957275 |
| Cellular Localisation | Golgi ApparatusCis-Golgi Network MembranePeripheral Membrane ProteinLumenal SideCytoplasmSecretedA Small Fraction Of The Protein May Be CytoplasmicIn Bone At Least Part Of It Is Found In The Extracellular Matrix And In The Culture Medium Of Calvaria ExplantsIn Lupus ProneBut Not In Normal MiceAt Least Part Of It Is In The Serum Where It Induces The Formation Of Autoantibodies Including Anti-Dna Antibodies |
| Alternative ELISA Names | Nucleobindin-1 ELISA kitCalnuc ELISA kitNucb1 ELISA kitNuc ELISA kitNucb ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
