• Mouse Low-density lipoprotein receptor/LDLR protein (Recombinant) (C-His) (STJP001498)

Mouse Low-density lipoprotein receptor/LDLR protein (Recombinant) (C-His) (STJP001498)

SKU:
STJP001498

£76.50 - £290.50
Current Stock:
Host: HEK293 cells
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Mouse Low-density lipoprotein receptor/LDLR-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Gene Symbol: Ldlr
Gene ID: 16835
Uniprot ID: LDLR_MOUSE
Immunogen: Recombinant Mouse Low-density lipoprotein receptor/LDLR Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala22-Arg790) of mouse LDLR/LDL Receptor (Accession #NP_034830.2) fused with a 6×His tag at
Function Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.
Protein Name Low-Density Lipoprotein Receptor
Ldl Receptor
Database Links Reactome: R-MMU-8856825
Reactome: -MMU-8856828
Reactome: -MMU-8964026
Reactome: -MMU-8964038
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Membrane
Clathrin-Coated Pit
Golgi Apparatus
Early Endosome
Late Endosome
Lysosome
Rapidly Endocytosed Upon Ligand Binding
Alternative Protein Names Low-Density Lipoprotein Receptor protein
Ldl Receptor protein
Ldlr protein

Information sourced from Uniprot.org

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