This Fndc5 Sandwich ELISA is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma and other biological fluids.
Applications
ELISA
Reactivity
Mouse
Sensitivity
37.5pg/mL
Detection Limit
62.5~4000pg/mL
Note
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Product Properties
Storage Instruction
If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
This kit recognizes Mouse FNDC5 in samples. No significant cross-reactivity or interference between Mouse FNDC5 and analogues was observed.
Sample Type
Serum, plasma and other biological fluids
Additional Info
Post Translational Modifications
The extracellular domain is cleaved and released from the cell membrane. N-Glycosylated.
Function
Irisin: Mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA.
Protein Name
Fibronectin Type Iii Domain-Containing Protein 5Fibronectin Type Iii Repeat-Containing Protein 2Peroxisomal ProteinPep Cleaved Into - Irisin
Cellular Localisation
Cell MembraneSingle-Pass Type I Membrane ProteinPeroxisome MembraneSecretedImported In Peroxisomes Through The Pex5 Receptor PathwayIrisin: SecretedDetected In The Blood Of Individuals Subjected To Endurance Exercise
Alternative ELISA Names
Fibronectin Type Iii Domain-Containing Protein 5 ELISA kitFibronectin Type Iii Repeat-Containing Protein 2 ELISA kitPeroxisomal Protein ELISA kitPep Cleaved Into - Irisin ELISA kitFndc5 ELISA kitFrcp2 ELISA kitPep ELISA kit
Specificity
This kit recognizes Mouse FNDC5 in samples. No significant cross-reactivity or interference between Mouse FNDC5 and analogues was observed.
