Mouse ADRb1 (Adrenergic Receptor Beta 1) Sandwich ELISA Kit (STJE0006960)
SPECIFICATIONS
General Information
| Short Description | This ADRb1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 0.059ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | Adrb1 |
| Gene ID | 11554 |
| Uniprot ID | ADRB1_MOUSE |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | In brain, expressed by glutamatergic and GABAergic neurons of the dorsal pons (at protein level). |
| Post Translational Modifications | Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase. |
| Function | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling. Involved in the regulation of sleep/wake behaviors. |
| Protein Name | Beta-1 Adrenergic ReceptorBeta-1 AdrenoreceptorBeta-1 Adrenoceptor |
| Database Links | Reactome: R-MMU-390696Reactome: -MMU-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEarly EndosomeColocalizes With Rapgef2 At The Plasma MembraneFound In The Golgi Upon Gopc Overexpression |
| Alternative ELISA Names | Beta-1 Adrenergic Receptor ELISA kitBeta-1 Adrenoreceptor ELISA kitBeta-1 Adrenoceptor ELISA kitAdrb1 ELISA kitAdrb1r ELISA kit |
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Information sourced from Uniprot.org