| Tissue Specificity | In brain, expressed by glutamatergic and GABAergic neurons of the dorsal pons (at protein level). |
| Post Translational Modifications | Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase. |
| Function | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling. Involved in the regulation of sleep/wake behaviors. |
| Protein Name | Beta-1 Adrenergic ReceptorBeta-1 AdrenoreceptorBeta-1 Adrenoceptor |
| Database Links | Reactome: R-MMU-390696Reactome: -MMU-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEarly EndosomeColocalizes With Rapgef2 At The Plasma MembraneFound In The Golgi Upon Gopc Overexpression |
| Alternative ELISA Names | Beta-1 Adrenergic Receptor ELISA kitBeta-1 Adrenoreceptor ELISA kitBeta-1 Adrenoceptor ELISA kitAdrb1 ELISA kitAdrb1r ELISA kit |
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Information sourced from Uniprot.org
