MASPIN Blocking Peptide peptide (STJ504955)
SPECIFICATIONS
ImmunogenSynthetic peptide taken within amino acid region 100-150 on human MASPIN protein.
General Information
| Short Description | MASPIN Blocking Peptide is synthetically produced from the 100-150 sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | SERPINB5 |
| Gene ID | 5268 |
| Uniprot ID | SPB5_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 100-150 on human MASPIN protein. |
| Immunogen Region | 100-150 |
Additional Info
| Tissue Specificity | Normal mammary epithelial cells. |
| Function | Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. |
| Peptide Name | Serpin B5MaspinPeptidase Inhibitor 5Pi-5 |
| Cellular Localisation | SecretedExtracellular Space |
| Alternative Peptide Names | Serpin B5 proteinMaspin proteinPeptidase Inhibitor 5 proteinPi-5 proteinSERPINB5 proteinPI5 protein |
Information sourced from Uniprot.org