Applications: |
Immunodepletion/Immunocompetition |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
MASPIN Blocking Peptide is synthetically produced from the 100-150 sequence and is suitable for use in western blot applications. |
Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
SERPINB5 |
Gene ID: |
5268 |
Uniprot ID: |
SPB5_HUMAN |
Immunogen Region: |
100-150 |
Immunogen: |
Synthetic peptide taken within amino acid region 100-150 on human MASPIN protein. |
Tissue Specificity | Normal mammary epithelial cells. |
Function | Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. |
Peptide Name | Serpin B5MaspinPeptidase Inhibitor 5Pi-5 |
Cellular Localisation | SecretedExtracellular Space |
Alternative Peptide Names | Serpin B5 proteinMaspin proteinPeptidase Inhibitor 5 proteinPi-5 proteinSERPINB5 proteinPI5 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance