Lysosomal acid lipase Positive Control for STJ507784 peptide (STJ507788)
SPECIFICATIONS
ImmunogenSynthetic peptide corresponding to amino acids within region 200-250 on Human Lysosomal acid lipase protein.
General Information
| Short Description | Lysosomal acid lipase Positive Control for STJ507784 is synthetically produced from the 200-250 sequence and is suitable for use in western blot applications. |
| Applications | WB |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | LIPA |
| Gene ID | 3988 |
| Uniprot ID | LICH_HUMAN |
| Immunogen | Synthetic peptide corresponding to amino acids within region 200-250 on Human Lysosomal acid lipase protein. |
| Immunogen Region | 200-250 |
| Specificity | This is positive control is recommended for use in combination with Lysosomal acid lipase antibody STJ507784. |
Additional Info
| Post Translational Modifications | Glycosylation is not essential for catalytic activity. |
| Function | Catalyzes the deacylation of cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol. Hydrolyzes triglycerides (1,2,3-triacylglycerol) and diglycerides (such as 1,2-diacylglycerol and 1,3-diacylglycerol) with preference for the acyl moieties at the sn-1 or sn-3 positions. |
| Peptide Name | Lysosomal Acid Lipase/Cholesteryl Ester HydrolaseAcid Cholesteryl Ester HydrolaseLalCholesteryl EsteraseDiacylglycerol LipaseLipase ASterol EsteraseTriacylglycerol Ester HydrolaseTriacylglycerol Lipase |
| Database Links | Reactome: R-HSA-8964038 |
| Cellular Localisation | Lysosome |
| Alternative Peptide Names | Lysosomal Acid Lipase/Cholesteryl Ester Hydrolase proteinAcid Cholesteryl Ester Hydrolase proteinLal proteinCholesteryl Esterase proteinDiacylglycerol Lipase proteinLipase A proteinSterol Esterase proteinTriacylglycerol Ester Hydrolase proteinTriacylglycerol Lipase proteinLIPA protein |
Information sourced from Uniprot.org