| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Lysosomal acid lipase Positive Control for STJ507784 is synthetically produced from the 200-250 sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
LIPA |
| Gene ID: |
3988 |
| Uniprot ID: |
LICH_HUMAN |
| Immunogen Region: |
200-250 |
| Specificity: |
This is positive control is recommended for use in combination with Lysosomal acid lipase antibody STJ507784. |
| Immunogen: |
Synthetic peptide corresponding to amino acids within region 200-250 on Human Lysosomal acid lipase protein. |
| Post Translational Modifications | Glycosylation is not essential for catalytic activity. |
| Function | Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol. |
| Peptide Name | Lysosomal Acid Lipase/Cholesteryl Ester HydrolaseAcid Cholesteryl Ester HydrolaseLalCholesteryl EsteraseLipase ASterol Esterase |
| Database Links | Reactome: R-HSA-8964038 |
| Cellular Localisation | Lysosome |
| Alternative Peptide Names | Lysosomal Acid Lipase/Cholesteryl Ester Hydrolase proteinAcid Cholesteryl Ester Hydrolase proteinLal proteinCholesteryl Esterase proteinLipase A proteinSterol Esterase proteinLIPA protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
