Human VCC1 (VEGF Co Regulated Chemokine 1) Sandwich ELISA Kit (STJE0012983)
SPECIFICATIONS
General Information
| Short Description | This VCC1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 4.7pg/mL |
| Detection Limit | 15.6-1000pg/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | CXCL17 |
| Gene ID | 284340 |
| Uniprot ID | CXL17_HUMAN |
| Sample Type | serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Additional Info
| Tissue Specificity | Detected in trachea, stomach, lung and skeletal muscle. Detected in intestine and in normal and asthmatic lung (at protein level). Breast tumors showed 3- to 24-fold up-regulation. |
| Post Translational Modifications | Likely to undergo an endoproteolytic process to form a four-cysteine-containing mature peptide with a canonical CXC chemokine scaffold after secretion. |
| Function | Chemokine that acts as a chemoattractant for monocytes, macrophages and dendritic cells. Plays a role in angiogenesis and possibly in the development of tumors. Acts as an anti-inflammatory in the stomach. May play a role in the innate defense against infections. Activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions. 4-Cys CXCL17: Seems to exhibit much higher chemoattractant potency on monocytes and macrophages than 6-Cys CXCL17. |
| Protein Name | C-X-C Motif Chemokine 176-Cys Cxcl17Dendritic Cell And Monocyte Chemokine-Like ProteinDmcVegf Coregulated Chemokine 1 Cleaved Into - 4-Cys Cxcl17 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | C-X-C Motif Chemokine 17 ELISA kit6-Cys Cxcl17 ELISA kitDendritic Cell And Monocyte Chemokine-Like Protein ELISA kitDmc ELISA kitVegf Coregulated Chemokine 1 Cleaved Into - 4-Cys Cxcl17 ELISA kitCXCL17 ELISA kitVCC1 ELISA kitUNQ473 ELISA kitPRO842 ELISA kit |
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Information sourced from Uniprot.org