| Tissue Specificity | Detected in trachea, stomach, lung and skeletal muscle. Detected in intestine and in normal and asthmatic lung (at protein level). Breast tumors showed 3- to 24-fold up-regulation. |
| Post Translational Modifications | Likely to undergo an endoproteolytic process to form a four-cysteine-containing mature peptide with a canonical CXC chemokine scaffold after secretion. |
| Function | Chemokine that acts as a chemoattractant for monocytes, macrophages and dendritic cells. Plays a role in angiogenesis and possibly in the development of tumors. Acts as an anti-inflammatory in the stomach. May play a role in the innate defense against infections. Activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions. 4-Cys CXCL17: Seems to exhibit much higher chemoattractant potency on monocytes and macrophages than 6-Cys CXCL17. |
| Protein Name | C-X-C Motif Chemokine 176-Cys Cxcl17Dendritic Cell And Monocyte Chemokine-Like ProteinDmcVegf Coregulated Chemokine 1 Cleaved Into - 4-Cys Cxcl17 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | C-X-C Motif Chemokine 17 ELISA kit6-Cys Cxcl17 ELISA kitDendritic Cell And Monocyte Chemokine-Like Protein ELISA kitDmc ELISA kitVegf Coregulated Chemokine 1 Cleaved Into - 4-Cys Cxcl17 ELISA kitCXCL17 ELISA kitVCC1 ELISA kitUNQ473 ELISA kitPRO842 ELISA kit |
| output | |
Information sourced from Uniprot.org
