Human UbcH6/UBE2E1 protein (Recombinant) (His-Tag) (STJP017799)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human UbcH6/UBE2E1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UBE2E1 |
| Gene ID | 7324 |
| Uniprot ID | UB2E1_HUMAN |
| Accession Number | NP_003332 |
| Immunogen | Human |
| Immunogen Region | 1-193aa |
| Immunogen Sequence |
Additional Info
| Post Translational Modifications | ISGylation suppresses ubiquitin E2 enzyme activity. Autoubiquitinated in vitro. |
| Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes the covalent attachment of ISG15 to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. In vitro also catalyzes 'Lys-48'-linked polyubiquitination. Catalyzes monoubiquitination of other proteins in both an E3-dependent and E3-independent manner. |
| Protein Name | Ubiquitin-Conjugating Enzyme E2 E1(E3-Independent E2 Ubiquitin-Conjugating Enzyme E1E2 Ubiquitin-Conjugating Enzyme E1Ubch6Ubiquitin Carrier Protein E1Ubiquitin-Protein Ligase E1 |
| Database Links | Reactome: R-HSA-1169408Reactome: R-HSA-141430Reactome: R-HSA-174048Reactome: R-HSA-174084Reactome: R-HSA-174154Reactome: R-HSA-174178Reactome: R-HSA-174184Reactome: R-HSA-176407Reactome: R-HSA-176408Reactome: R-HSA-176409Reactome: R-HSA-176412Reactome: R-HSA-179409Reactome: R-HSA-2467813Reactome: R-HSA-2559582Reactome: R-HSA-68867Reactome: R-HSA-69017Reactome: R-HSA-8853884Reactome: R-HSA-8866652Reactome: R-HSA-8866654Reactome: R-HSA-9687136Reactome: R-HSA-983168 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Ubiquitin-Conjugating Enzyme E2 E1 protein(E3-Independent E2 Ubiquitin-Conjugating Enzyme E1 proteinE2 Ubiquitin-Conjugating Enzyme E1 proteinUbch6 proteinUbiquitin Carrier Protein E1 proteinUbiquitin-Protein Ligase E1 proteinUBE2E1 proteinUBCH6 protein |
Information sourced from Uniprot.org