Human TRPC1 protein (Recombinant) (N-His) (STJP008094)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human TRPC1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | TRPC1 |
| Gene ID | 7220 |
| Uniprot ID | TRPC1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Thr45-Lys386 |
Additional Info
| Post Translational Modifications | Activation of PRKCA induces phosphorylation of TRPC1 and subsequent Ca2+ entry into cells. |
| Function | Forms a receptor-activated non-selective calcium permeant cation channel. Forms a heteromeric ion channel with TRPC4 or TRPC5 that has reduced calcium permeability compared to the homomeric TRPC4 or TRPC5 channel. Also permeable to monovalent ions including sodium, lithium and cesium ions. Isoform Short: Forms a receptor-activated non-selective calcium permeant cation channel. Also activated by intracellular calcium store depletion. |
| Protein Name | Short Transient Receptor Potential Channel 1Trpc1Transient Receptor Protein 1Trp-1 |
| Database Links | Reactome: R-HSA-3295583Reactome: R-HSA-418890Reactome: R-HSA-5578775Reactome: R-HSA-983695 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | Short Transient Receptor Potential Channel 1 proteinTrpc1 proteinTransient Receptor Protein 1 proteinTrp-1 proteinTRPC1 proteinTRP1 protein |
Information sourced from Uniprot.org