Human TRPC1 protein (Recombinant) (N-His) (STJP008094)

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STJP008094
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human TRPC1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: TRPC1
Gene ID: 7220
Uniprot ID: TRPC1_HUMAN
Immunogen Region: Thr45-Lys386
Immunogen: Homo sapiens (Human)
Post Translational Modifications Activation of PRKCA induces phosphorylation of TRPC1 and subsequent Ca2+ entry into cells.
Function Forms a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Also activated by intracellular calcium store depletion. Isoform Short: Forms a receptor-activated non-selective calcium permeant cation channel. Also activated by intracellular calcium store depletion.
Protein Name Short Transient Receptor Potential Channel 1
Trpc1
Transient Receptor Protein 1
Trp-1
Database Links Reactome: R-HSA-3295583
Reactome: R-HSA-418890
Reactome: R-HSA-5578775
Reactome: R-HSA-983695
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Short Transient Receptor Potential Channel 1 protein
Trpc1 protein
Transient Receptor Protein 1 protein
Trp-1 protein
TRPC1 protein
TRP1 protein

Information sourced from Uniprot.org

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