Human TOMM20 protein (Recombinant) (His-Tag) (STJP018219)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human TOMM20-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% Glycerol, 2mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TOMM20 |
| Gene ID | 9804 |
| Uniprot ID | TOM20_HUMAN |
| Accession Number | NP_055580 |
| Immunogen | Human |
| Immunogen Region | 25-145aa |
| Immunogen Sequence |
Additional Info
| Post Translational Modifications | Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30. |
| Function | Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore. Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases. |
| Protein Name | Mitochondrial Import Receptor Subunit Tom20 HomologMitochondrial 20 Kda Outer Membrane ProteinOuter Mitochondrial Membrane Receptor Tom20 |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-5205685Reactome: R-HSA-5689880 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Membrane Protein |
| Alternative Protein Names | Mitochondrial Import Receptor Subunit Tom20 Homolog proteinMitochondrial 20 Kda Outer Membrane Protein proteinOuter Mitochondrial Membrane Receptor Tom20 proteinTOMM20 proteinKIAA0016 protein |
Information sourced from Uniprot.org