Human TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily Member 1b) Antibody Pair (STJAP00210)

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STJAP00210-50
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Host: Mouse/Goat
Applications: ELISA
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description : This TNFRSF1B antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA.
Clonality : Monoclonal/Polyclonal
Conjugation: Unconjugated/Biotin
Formulation: Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Purification: Capture Purification: Protein A or G.
Detection Purification: Antigen Affinity.
Concentration: 0.5 mg/mL
Storage Instruction: Store at-20°C for long term, and avoid freeze-thaw cycles.
Gene Symbol: TNFRSF1B
Gene ID: 7133
Uniprot ID: TNR1B_HUMAN
Immunogen: Capture immunogen: Recombinant Human TNFRSF1B protein.
Detection Immunogen: Recombinant Human TNFRSF1B protein.
Function Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 1b
Tumor Necrosis Factor Receptor 2
Tnf-R2
Tumor Necrosis Factor Receptor Type Ii
Tnf-Rii
Tnfr-Ii
P75
P80 Tnf-Alpha Receptor
Cd Antigen Cd120b
Etanercept Cleaved Into - Tumor Necrosis Factor Receptor Superfamily Member 1b - Membrane Form - Tumor Necrosis Factor-Binding Protein 2
Tbp-2
Tbpii
Database Links Reactome: R-HSA-5668541
Reactome: R-HSA-5669034
Reactome: R-HSA-6783783
Reactome: R-HSA-6785807
Reactome: R-HSA-6798695
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Secreted
Tumor Necrosis Factor-Binding Protein 2: Secreted
Alternative Antibody Pair Names Tumor Necrosis Factor Receptor Superfamily Member 1b antibody pair
Tumor Necrosis Factor Receptor 2 antibody pair
Tnf-R2 antibody pair
Tumor Necrosis Factor Receptor Type Ii antibody pair
Tnf-Rii antibody pair
Tnfr-Ii antibody pair
P75 antibody pair
P80 Tnf-Alpha Receptor antibody pair
Cd Antigen Cd120b antibody pair
Etanercept Cleaved Into - Tumor Necrosis Factor Receptor Superfamily Member 1b - Membrane Form - Tumor Necrosis Factor-Binding Protein 2 antibody pair
Tbp-2 antibody pair
Tbpii antibody pair
TNFRSF1B antibody pair
TNFBR antibody pair
TNFR2 antibody pair

Information sourced from Uniprot.org

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