Human TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily Member 1b) Antibody Pair (STJAP00210)
SPECIFICATIONS
ClonalityMonoclonal/Polyclonal
HostMouse/Goat
ConjugationUnconjugated/Biotin
ImmunogenCapture immunogen: Recombinant Human TNFRSF1B protein.Detection Immunogen: Recombinant Human TNFRSF1B protein.
General Information
| Short Description | This TNFRSF1B antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Mouse/Goat |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Polyclonal |
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Protein A or G.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | TNFRSF1B |
| Gene ID | 7133 |
| Uniprot ID | TNR1B_HUMAN |
| Immunogen | Capture immunogen: Recombinant Human TNFRSF1B protein.Detection Immunogen: Recombinant Human TNFRSF1B protein. |
Additional Info
| Function | Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 1bTumor Necrosis Factor Receptor 2Tnf-R2Tumor Necrosis Factor Receptor Type IiTnf-RiiTnfr-IiP75P80 Tnf-Alpha ReceptorCd Antigen Cd120bEtanercept Cleaved Into - Tumor Necrosis Factor Receptor Superfamily Member 1b - Membrane Form - Tumor Necrosis Factor-Binding Protein 2Tbp-2Tbpii |
| Database Links | Reactome: R-HSA-5668541Reactome: R-HSA-5669034Reactome: R-HSA-6783783Reactome: R-HSA-6785807Reactome: R-HSA-6798695 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: SecretedTumor Necrosis Factor-Binding Protein 2: Secreted |
| Alternative Antibody Pair Names | Tumor Necrosis Factor Receptor Superfamily Member 1b antibody pairTumor Necrosis Factor Receptor 2 antibody pairTnf-R2 antibody pairTumor Necrosis Factor Receptor Type Ii antibody pairTnf-Rii antibody pairTnfr-Ii antibody pairP75 antibody pairP80 Tnf-Alpha Receptor antibody pairCd Antigen Cd120b antibody pairEtanercept Cleaved Into - Tumor Necrosis Factor Receptor Superfamily Member 1b - Membrane Form - Tumor Necrosis Factor-Binding Protein 2 antibody pairTbp-2 antibody pairTbpii antibody pairTNFRSF1B antibody pairTNFBR antibody pairTNFR2 antibody pair |
Information sourced from Uniprot.org