Human TMED9 protein (Recombinant) (N-His) (STJP009707)

SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
STJP009707
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General Information

Short DescriptionRecombinant-Human TMED9-N-His protein was developed from e.coli for the region N-His. For use in research applications.
ApplicationsELISA/Immunogen/SDS-PAGE/WB
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeReconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
FormulationLyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Target Information

Gene SymbolTMED9
Gene ID54732
Uniprot IDTMED9_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionLeu38-Gly146

Additional Info

Function Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to membranes of the early secretory pathway. Increases coatomer-dependent activity of ARFGAP2. Thought to play a crucial role in the specific retention of p24 complexes in cis-Golgi membranes.specifically contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. May be involved in organization of intracellular membranes, such as of the ER-Golgi intermediate compartment and the Golgi apparatus. Involved in ER localization of PTPN2 isoform PTPB.
Protein Name Transmembrane Emp24 Domain-Containing Protein 9
Gmp25
Glycoprotein 25l2
P24 Family Protein Alpha-2
P24alpha2
P25
Database Links Reactome: R-HSA-6807878
Reactome: R-HSA-6811434
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type I Membrane Protein
Golgi Apparatus
Cis-Golgi Network Membrane
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Trans-Golgi Network Membrane
Cycles Between Compartments Of The Early Secretatory Pathway
Alternative Protein Names Transmembrane Emp24 Domain-Containing Protein 9 protein
Gmp25 protein
Glycoprotein 25l2 protein
P24 Family Protein Alpha-2 protein
P24alpha2 protein
P25 protein
TMED9 protein
GP25L2 protein

Information sourced from Uniprot.org

Citations

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