| Function | Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to membranes of the early secretory pathway. Increases coatomer-dependent activity of ARFGAP2. Thought to play a crucial role in the specific retention of p24 complexes in cis-Golgi membranes.specifically contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. May be involved in organization of intracellular membranes, such as of the ER-Golgi intermediate compartment and the Golgi apparatus. Involved in ER localization of PTPN2 isoform PTPB. |
| Protein Name | Transmembrane Emp24 Domain-Containing Protein 9Gmp25Glycoprotein 25l2P24 Family Protein Alpha-2P24alpha2P25 |
| Database Links | Reactome: R-HSA-6807878Reactome: R-HSA-6811434 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type I Membrane ProteinGolgi ApparatusCis-Golgi Network MembraneEndoplasmic Reticulum-Golgi Intermediate Compartment MembraneTrans-Golgi Network MembraneCycles Between Compartments Of The Early Secretatory Pathway |
| Alternative Protein Names | Transmembrane Emp24 Domain-Containing Protein 9 proteinGmp25 proteinGlycoprotein 25l2 proteinP24 Family Protein Alpha-2 proteinP24alpha2 proteinP25 proteinTMED9 proteinGP25L2 protein |
Information sourced from Uniprot.org
