Human SUPV3L1 protein (Recombinant) (N-His) (STJP010967)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human SUPV3L1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | SUPV3L1 |
| Gene ID | 6832 |
| Uniprot ID | SUV3_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Thr47-Glu722 |
Additional Info
| Function | Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria.regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA. |
| Protein Name | Atp-Dependent Rna Helicase Supv3l1 - MitochondrialSuppressor Of Var1 3-Like Protein 1Suv3-Like Protein 1 |
| Database Links | Reactome: R-HSA-9836573 |
| Cellular Localisation | NucleusMitochondrion MatrixMitochondrion Nucleoid |
| Alternative Protein Names | Atp-Dependent Rna Helicase Supv3l1 - Mitochondrial proteinSuppressor Of Var1 3-Like Protein 1 proteinSuv3-Like Protein 1 proteinSUPV3L1 proteinSUV3 protein |
Information sourced from Uniprot.org