Human STEAP4 protein (Recombinant) (N-His) (STJP007466)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human STEAP4-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | STEAP4 |
| Gene ID | 79689 |
| Uniprot ID | STEA4_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Thr21-Gln195 |
Additional Info
| Function | Integral membrane protein that functions as a NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound on the other side of the membrane. Mediates sequential transmembrane electron transfer from NADPH to FAD and onto heme, and finally to the Fe(3+) chelate. Can also reduce Cu(2+) to Cu(1+). Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses. Associated with obesity and insulin-resistance. Involved in inflammatory arthritis, through the regulation of inflammatory cytokines. Inhibits anchorage-independent cell proliferation. |
| Protein Name | Metalloreductase Steap4Six-Transmembrane Epithelial Antigen Of Prostate 4Sixtransmembrane Protein Of Prostate 2Tumor Necrosis Factor - Alpha-Induced Protein 9 |
| Database Links | Reactome: R-HSA-917977 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinGolgi Apparatus MembraneEarly Endosome Membrane |
| Alternative Protein Names | Metalloreductase Steap4 proteinSix-Transmembrane Epithelial Antigen Of Prostate 4 proteinSixtransmembrane Protein Of Prostate 2 proteinTumor Necrosis Factor - Alpha-Induced Protein 9 proteinSTEAP4 proteinSTAMP2 proteinTNFAIP9 protein |
Information sourced from Uniprot.org