Human SLC13A3 protein (Recombinant) (N-His-KSI) (STJP016139)

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STJP016139
€250.20 - €1,396.20
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Short Description :Recombinant-Human SLC13A3-N-His-KSI protein was developed from e.coli for the region N-His-KSI. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:Please contact us for further information.
Gene Symbol:SLC13A3
Gene ID:64849
Uniprot ID:S13A3_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Ile158-Ile230
Function High-affinity sodium-dicarboxylate cotransporter that accepts a range of substrates with 4-6 carbon atoms, such as the citric acid cycle intermediates succinate and alpha-ketoglutarate (2-oxoglutarate), as well as other compounds including N-acetyl-L-aspartate. Transports the dicarboxylate into the cell with a probable stoichiometry of 3 Na(+) for 1 divalent dicarboxylate, rendering the process electrogenic. Can transport citrate in a Na(+)-dependent manner, recognizing the divalent form of citrate rather than the trivalent form which is normally found in blood. Imports itaconate in hepatocytes leading to activation of TFEB-dependent lysosomal biogenesis involved in antibacterial innate immune response.
Protein Name Na(+/Dicarboxylate Cotransporter 3
Nadc-3
Hnadc3
Na(+-Coupled Carboxylate Transporter 3
Nac3
Sodium-Dependent High-Affinity Dicarboxylate Transporter 2
Solute Carrier Family 13 Member 3
Slc13a3
Database Links Reactome: R-HSA-433137
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Na(+/Dicarboxylate Cotransporter 3 protein
Nadc-3 protein
Hnadc3 protein
Na(+-Coupled Carboxylate Transporter 3 protein
Nac3 protein
Sodium-Dependent High-Affinity Dicarboxylate Transporter 2 protein
Solute Carrier Family 13 Member 3 protein
Slc13a3 protein
SLC13A3 protein
NADC3 protein
SDCT2 protein

Information sourced from Uniprot.org