Host: |
HEK293 cells |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Human SIRP-beta-1/SIRPB1/CD172b-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Gene Symbol: |
SIRPB1 |
Gene ID: |
10326 |
Uniprot ID: |
SIRB1_HUMAN |
Immunogen: |
Recombinant Human SIRP-beta-1/SIRPB1/CD172b Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu30-Leu371) of human SIRPB1/CD172b (Accession #NP_006056.2) fused with a 6Ă—His tag at the C-terminus. |
Post Translational Modifications | N-glycosylated. |
Function | Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP. |
Protein Name | Signal-Regulatory Protein Beta-1Sirp-Beta-1Cd172 Antigen-Like Family Member BCd Antigen Cd172b |
Database Links | Reactome: R-HSA-2172127Reactome: R-HSA-391160Reactome: R-HSA-6798695 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Protein Names | Signal-Regulatory Protein Beta-1 proteinSirp-Beta-1 proteinCd172 Antigen-Like Family Member B proteinCd Antigen Cd172b proteinSIRPB1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance